A 59-year-old woman presents to the ED feeling generally unwell with 2 months of worsening lethargy, nausea, generalized abdominal pain, and constipation. She is a heavy smoker and has hypertension, high cholesterol, and chronic bronchitis. She takes amlodipine 5mg daily and atorvastatin 40mg daily with no recent changes in doses or frequency. The patient has lost 15lbs despite a normal appetite over this period. There has been no recent exacerbation of her chronic cough. She had a few episodes of minimal hemoptysis a few months ago but none since. Vital signs are within normal limits. Auscultation of the lungs reveals mild decreased air entry throughout and no adventitious sounds. Mild generalized abdominal tenderness to palpation is noted. Physical examination is otherwise unremarkable. Laboratory investigations are notable for a Crof 0.8 and Ca of 12.1. Albumin is 3.8. Chest radiograph shows a discrete mass in the right hilum that is approximately 10mm in diameter; otherwise, lung fields are clear without collapse or consolidation. What is the best initial management of this patient?
A) Zoledronic acid 4mg IV
B) IV hydration with normal saline
C) IV hydration with 5% dextrose
D) Hydrochlorothiazide 12.5mg tablet



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