Janet is a 43-year-old patient with bipolar disorder. She is currently depressed with some features of hypomania. Practice guidelines recommend treatment with an antidepressant in patients with bipolar disorder under the following conditions:
A. As adjunct for acute bipolar I or II depressive episode with ≥2 concomitant manic symptoms, psychomotor agitation, or rapid cycling
B. During manic and depressive episodes with mixed features
C. In patients with predominantly mixed states
D. All of the above
E. None of the above