Which of the following is true regarding Zika virus and congenital Zika syndrome (CZS)?
a. CZS pathology is most likely driven by ZIKV tropism for fetal brain cells
b. CZS is less likely to occur if a woman becomes infected early during pregnancy
c. None are true
d. Pre-existing immunity to Zika doesn't reduce the risk of CZS
e. Congenital Zika virus infection causes neonatal liver disease