PICO is a mnemonic used to describe the four elements of a good clinical research question. PICO stands for: A. P = Population; I = Intervention; C = Comparison; O = Outcome B. P = Population; I = Intervention; C = Confounding; O = Outcome C. P = P-value; I = Inference; C = Confounding; O = Outcome D. P = P-value; I = Intervention; C = Comparison; O = Outcome