There are several types of voltage-activated channels. For ex: Na+, K+, Ca+, and Cl-.Voltage gated --- channels initiate action potentials in the axons of nerves and muscle cells-when activated, depolarize the mb from --- (resting potential) up to ---. Channel can then become --- (---) and incapable of opening until reset (---)-drugs can have greater affinity for certain conformations ie. ---. For example, local anesthetics and antiarrhythmics-local anesthetics eg. lidocaine bind to the channel to prolong the --- ---