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Mutations can alter the function of an operon. Predict how the following mutations would
affect the Lac Operon function (a) in the presence of lactose or (b) in the absence of
lactose. Will the genes be transcribed or not?
A. Mutation of the Operator so that the repressor can no longer bind to it.
B. Mutation of the Promoter, Ples, so that it is no longer seen by RNA polymerase.
C. Mutation of the Promoter, PI, so that it is no longer bound by RNA polymerase.
D. Mutation of the Repressor so that it cannot bind to lactose.
E. Mutation of the Repressor so that it cannot bind to the Operator.



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