Answer:
Option 4, Graves' disease
Explanation:
Graves' disease is an autoimmune disorder characterized by hyperthyroidism, a condition in which the thyroid gland produces an excess supply of thyroid hormones, which are responsible for increasing the metabolism, growth and maturation of cells, and increasing sensitivity to the catecholamine neurotransmitters (e.g. norepinephrine, dopamine) which prepare the body for sympathetic nervous system stimulation (fight-or-flight response).
As a result, the patient may develop a goiter, a visibly-enlarged thyroid gland, and exhibit symptoms reflecting this increased metabolic demand, like diaphoresis (sweating), muscle wasting, weight loss, hair thinning, tremors, diarrhea, and more.
In short, an overproduction of thyroid hormone results in Graves' disease, Option 4.