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A female, on hormonal contraceptives, missed her period but tested negative for pregnancy. Which of the following describes the changes during her follicular phase?

A. High concentration of estrogen stimulated the hypothalamus to release GnRH.
B. Constant low levels of estrogen inhibit LH secretion, preventing ovulation.
C. Synthetic estradiol caused thickening of the endometrial lining.
D. High concentration of estrogen stimulated the pituitary gland to release LH and FSH.



Answer :

Final answer:

During the follicular phase, high estrogen levels stimulate the hypothalamus to release GnRH.


Explanation:

High concentration of estrogen stimulated the hypothalamus to release GnRH. This occurs during the follicular phase of the menstrual cycle when the ovaries produce estrogen, leading to the stimulation of GnRH secretion.


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